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apalutamide will lower the level or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a solid CYP3A4 inducer, with drugs which can be CYP3A4 substrates may end up in reduced publicity to those drugs.Diazepam may be quantified in blood or plasma to verif